It has diverse biological effects. ghrelin stimulates food intake and regulates energy homeostasis through activating the expression of the orexigenic neuropeptides NPY ( neuropeptide Y)/ AGRP ( agouti-related protein) in hypothalamic neurons, by which it plays a key role in obesity pathogenesis. 它通过激活下丘脑神经元表达促胃肽NPY(神经肽Y)/AGRP(刺鼠相关蛋白)来促进摄食和调节能量平衡,在肥胖的发病机制中起重要作用。
Effects of dietary on hypothalamic neuropeptide Y gene expression and obesity in rats 饮食对下丘脑神经肽Y基因表达及肥胖影响
Analysis on the Relevant Factors Involving the Effect of Acupuncture in Improving Lipo-metabolism in Hypothalamic Obesity Rats 针刺影响下丘脑性肥胖大鼠脂代谢相关因素的分析
Effect of Acupuncture on the Contents of Hypothalamic Neuropeptides in Obesity Rats 针刺对肥胖大鼠下丘脑神经肽含量的影响